Diarrhea in rabbits following oro-gastric inoculation of <i>V. parahaemolyticus</i> or one of its isogenic derivatives.

aAll strains are derivatives of V. parahaemolyticus RMID2210633 (WT); mutants contain the following gene deletions - TDH (ΔtdhAS), T3SS1 (ΔvscN1), T3SS2 (ΔvscN2) and triple (ΔtdhAS ΔvcrD1 ΔvcrD2). bPercentage of rabbits by 38 hr PI that had yellow, watery diarrhea. cThe proportion of rabbits with diarrhea was significantly (P<0.05; Fishers exact test) lower when infected with the T3SS1 mutant compared to the wild type. dNumber of rabbits within each disease category as described in the methods. eFluid accumulation ratio (FAR) of all infected (living) rabbits within the group (mean ± SD). FARs of wild type or mock infected rabbits were compared to mutants using one way ANOVA with Bonferroni's multiple comparison test.