Human Protein Atlas - Tissue Atlas

The Tissue Atlas contains information regarding the expression profiles of human genes both on the mRNA and protein level. The protein expression data from 44 normal human tissue types is derived from antibody-based protein profiling using immunohistochemistry . All underlying images of immunohistochemistry stained normal tissues are available together with knowledge-based annotation of protein expression levels. The protein data covers 15313 genes (78%) for which there are available antibodies. The mRNA expression data is derived from deep sequencing of RNA (RNA-seq) from 37 different normal tissue types.

该组织图谱包含了人类基因在mRNA和蛋白质水平上的表达谱信息。44种正常人类组织的蛋白质表达数据是通过基于抗体的蛋白质分析，即免疫组化技术获得的。所有免疫组化染色的正常组织图像及其蛋白质表达水平的知识库注释均一并提供。蛋白质数据涵盖了15313个基因（占总数的78%），对于这些基因均有可用的抗体。mRNA表达数据则是通过对37种不同正常组织类型的RNA进行深度测序（RNA-seq）所得。

搜集汇总

背景与挑战

背景概述

Human Protein Atlas - Tissue Atlas 数据集提供了人类基因在蛋白质和mRNA水平的全面表达谱信息，覆盖44种正常组织类型的蛋白质数据（基于免疫组化，涉及15313个基因）和37种组织的mRNA数据（基于RNA测序）。其特点在于整合了多层次的生物分子数据，并包含详细的图像和注释，支持生物医学研究中的基因表达分析。