Ragulator binds Rag dimers
收藏reactome.org2025-01-22 收录
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A complex of LAMTOR1-5, known as Ragulator, interacts with Rag GTPases, recruiting them to lysosomes, an essential step in mTORC1 activation by amino acids (Sancak et al. 2010).
LAMTOR1-5复合体,又称Ragulator,与Rag GTP酶相互作用,将其招募至溶酶体,这是通过氨基酸激活mTORC1的关键步骤(Sancak等,2010年)。
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