five

Identification of Ligand-Receptor Pairs that Drive Human Astrocyte Development

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP396908
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We tested a group of five neuronally-secreted ligands and validated their synergistic contributions to astrocyte development within both human cortical organoids and primary fetal tissue. Overall design: We performed differential gene expression and fold change analysis using data obtained from targeted and bulk RNA-seq of purified fetal astrocyte cell cultures and 3 different organoid lines at three time points.
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2024-05-18
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