Crystal Structure of S.A. gyrase-AM8191 complex
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Crystal Structure of S.A. gyrase-AM8191 complex Descriptor: 6-[({(1r,4S)-1-[(1S)-2-(3-fluoro-6-methoxy-1,5-naphthyridin-4-yl)-1-hydroxyethyl]-2-oxabicyclo[2.2.2]oct-4-yl}amino)methyl]-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one, Chimera protein of DNA gyrase subunits B and A, DNA (5'-D(P*AP*GP*CP*CP*GP*TP*AP*GP*GP*GP*CP*CP*CP*TP*AP*CP*GP*GP*CP*T)-3'), ... Authors: Lu, J, Patel, S, Soisson, S. Deposit date: 2014-05-16 Release date: 2014-06-18 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.69 Å) Cite: Oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad spectrum antibacterial agents. Acs Med.Chem.Lett., 5, 2014
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2014-05-16
