Distribution of MMP-1 paired loci polymorphisms with increasing order of variant alleles and association with the gastric cancer risk.

OR, odds ratio; CI, confidence interval; Ref, reference. 0 = no risk allele for both loci, 1 = one risk allele for any one loci, 2 = two risk allele for both the loci, 3 = one risk allele for any one locus and two risk allele for another locus, 4 = All risk allele for both the loci. Adjusted OR calculated for age, sex, addiction, by binary logistic regression model using SPSS v16.0 software. P value is for χ2-test showing the significance of difference in the distributions of the variant alleles between patients and controls. Values in bold indicate positive significance (P<0.05). No risk allele for both the gene was taken as reference to calculate OR. (*) OR not calculated because of very low frequency in both control and patient population.