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Myelodysplastic syndrome: NUP98-HoxD13 (NHD13) expression effect on hematopoietic stem cells

ChEBI2016-07-03 更新2026-07-12 收录

骨髓增生异常综合征

造血干细胞功能

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-66264 数据链接链接失效反馈

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资源简介：

Myelodysplastic syndrome: NUP98-HoxD13 (NHD13) expression effect on hematopoietic stem cells

应用场景：

创建时间：

2016-07-03

铜缺乏症

骨髓增生异常综合征

While copper deficiency is rare, it can have serious consequences, including pancytopenia and neuropathy. This treatable vitamin deficiency can present very similarly to myelodysplastic syndrome (MDS)

DataCite Commons2023-07-22 更新80

Gene expression profile of HSPC with cell-intrinsic innate immune signaling activation after LPS treatment

造血干细胞基因表达

骨髓增生异常综合征

The underlying mechanisms responsible for the competitive advantage of MDS HSPC in an inflammatory milieu remains poorly defined. Here, we show that MDS HPSC are protected from low-grade chronic infla

NIAID Data Ecosystem50

STAT1 is essential for hematopoietic stem cell function and maintains a MHC IIhi stem cell subset that resists myeloablation and neoplastic expansion [LK]

造血干细胞功能

STAT1基因

Adult hematopoietic stem cells (HSCs) are predominantly quiescent and can be activated in response to acute stress such as infection or cytotoxic insults. STAT1 is a pivotal mediator of interferon (I

NIAID Data Ecosystem40

MDS in Humanized Mice. MDS in Humanized Mice

骨髓增生异常综合征

异种移植基因组学

This study was to develop a faithful pre-clinical MDS patient-derived xenotransplantation model in cytokine-humanized immunodeficient "MISTRG" mice. We performed targeted genome sequencing on bone mar

NIAID Data Ecosystem70

General characteristics of the whole MDS population as compared to a reference group with normal serum iron indices and hepcidin.

骨髓增生异常综合征

铁代谢指标

*: geometric means with 95% Confidence Intervals between bracke.

Figshare2015-12-02 更新40