Voltage imaging in zebrafish spinal cord with zArchon1

Glutamatergic neurons in the zebrafish ventral spinal cord expressing zArchon1 were imaged via light sheet fluorescence microscopy. The data has been used to test the <i>in vivo</i> voltage imaging signal extraction pipeline, Spike-Guided Penalized Matrix Decomposition-Nonnegative Matrix Factorization (SGPMD-NMF).<br>The experimental method is described in:<br>Xie et al., High-fidelity estimates of spikes and subthreshold waveforms from 1-photon voltage imaging <i>in vivo</i>, Cell Reports (2021), https://doi.org/10.1016/j.celrep.2021.108954.