Most Notable Off-Target Effects of FDA-Approved Drugs.

NIAID Data Ecosystem2026-03-06 收录

药物脱靶效应

药物警戒分析

数据链接：

https://figshare.com/articles/dataset/_Most_Notable_Off_Target_Effects_of_FDA_Approved_Drugs_/594796 数据链接链接失效反馈

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资源简介：

*Italics = unique enrichment among FDA-approved drugs.

创建时间：

2008-08-08

Adverse events associated with acute pancreatitis caused by immune checkpoint inhibitors: a pharmacovigilance analysis of the FDA adverse event reporting system (FAERS) database

药物警戒分析

免疫检查点抑制剂不良反应

The precise incidence of immune-related adverse events (irAEs) remains unclear. This pharmacovigilance study investigated acute pancreatitis (AP) associated with immune checkpoint inhibitors (ICIs) us

Figshare2025-03-28 更新60

Analysis of the relationship between histamine H1 receptor antagonists and broad dementia events using the FAERS, JADER, and CVAR databases

药物警戒分析

神经药理学风险

Recent studies suggest histamine H1 receptor antagonists (H1RAs) may elevate broad dementia events risk, though real-world data remain scarce. This pharmacovigilance study analyzed FDA Adverse Event

NIAID Data Ecosystem20

Supplementary Dataset: Metagenomic-assembled genomes for the paper "Combined high-quality metagenomics reveals off-target effects of albendazole, ivermectin-albendazole and moxidectin-albendazole on the human gut bacteria."

微生物组

药物脱靶效应

In the framework of a randomized-controlled trial we collected stool samples of 204 Trichuris sp.-infected individuals in Côte d’Ivoire receiving albendazole (400mg), ivermectin-albendazole (200µg/kg/

Zenodo2026-05-22 更新00

Proportional imbalance method four-cell table.

药物警戒分析

免疫治疗不良反应

With the extensive clinical application of immune checkpoint inhibitors (ICIs), immune-related adverse events (irAEs) associated with these agents have increasingly garnered significant attention. Unl

NIAID Data Ecosystem30

Top 20 ranked putative off-targets of PDE3B.

药物脱靶效应

分子对接

Docking score that is less than -7.5 is highlighted in bold.

Figshare2019-06-17 更新10