A: Lung wet-to-dry weight ratio of the left lung of PVM-infected mice that received 20 µg of TIP in 30 µl saline or 30 µl saline on day seven after infection and were studied two, four or six hours la
*IC50 values reflect concentration of Tfab required to compete 50% of saturating Tmab IgG. Errors are standard deviations from technical triplicates. In vitro binding affinity of Tfab and Tmab.
Association (Kon) and dissociation (Koff) rate constants for purified MAb DB81 were measured by surface plasmon resonance. The Kd was calculated as Koff\\Kon.