Genome-wide analysis for joint tissues of Fas (ligand) mutant mice during autoantibody induced arthritis. Genome-wide analysis for joint tissues of Fas (ligand) mutant mice during autoantibody induced arthritis

Analysis on gene expression between RA-induced WT, Fas^lpr/lpr, and Fas^gld/gld mice. Data shows different expression pattern between Fas^gld/gld joint and Fas^lpr/lpr(or WT) mice. The reseults indicate sFasL-dependent, but Fas-independent gene expression during AIA Overall design: Total RNA obtained from mouse joint tissues from K/BxN sera(100uL x 2 times) injected C57BL/6, Fas^lpr/lpr, and Fas^gld/gld mice. Harvested at day 10