Crystal structure of MKK7 (MAP2K7) with ibrutinib bound at allosteric site
收藏Protein Data Bank Japan2024-01-24 更新2026-03-21 收录
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Crystal structure of MKK7 (MAP2K7) with ibrutinib bound at allosteric site Descriptor: 1,2-ETHANEDIOL, 1-{(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl}prop-2-en-1-one, DIMETHYL SULFOXIDE, ... Authors: Chaikuad, A, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2020-05-06 Release date: 2020-08-12 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Catalytic Domain Plasticity of MKK7 Reveals Structural Mechanisms of Allosteric Activation and Diverse Targeting Opportunities. Cell Chem Biol, 27, 2020
创建时间：
2020-05-06
