Coagulation and Platelet Parameters.
收藏Figshare2026-01-21 更新2026-04-28 收录
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Type 2 diabetes mellitus (T2DM) is associated with a prothrombotic state; however, its hemostatic profile in conflict-affected populations remains poorly characterized. This study aimed to evaluate coagulation parameters and platelet indices among Yemeni adults with T2DM and to correlate these markers with glycemic control. A case-control study was conducted on 140 T2DM patients and 100 age- and sex-matched non-diabetic controls in Aden, Yemen. Prothrombin time (PT), activated partial thromboplastin time (APTT), mean platelet volume (MPV), and platelet distribution width (PDW) were measured using standardized analyzers (STA-R Evolution and Sysmex XN-550). Glycemic control was assessed via HbA1c. Poor glycemic control (HbA1c ≥ 7%) was observed in 86% of patients. T2DM patients exhibited a distinct coagulation profile: prolonged PT (13.4 ± 1.8 vs. 12.1 ± 1.2 sec, p
创建时间：
2026-01-21
