相关数据集
Data from: Candidate risk factors and mechanisms for tolvaptan-induced liver injury are identified using a collaborative cross approach
Clinical trials of tolvaptan showed it to be a promising candidate for the treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD) but also revealed potential for idiosyncratic drug-induced
DataONE2016-12-20 更新100
Data from: Candidate risk factors and mechanisms for tolvaptan-induced liver injury are identified using a collaborative cross approach
Clinical trials of tolvaptan showed it to be a promising candidate for the treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD) but also revealed potential for idiosyncratic drug-induced
DataONE2016-12-20 更新70
In vivo transcriptomic responses to thioacetamide exposure in guinea pig liver tissue
In this study we tested the ability to predict organ injury from transcriptomic data in Hartley guinea pigs at early time points after exposure to thioacetamide (9 and 33 hours). We selected thioaceta
NIAID Data Ecosystem40
Candidate risk factors and mechanisms for tolvaptan-induced liver injury are identified using a collaborative cross approach
Clinical trials of tolvaptan showed it to be a promising candidate for the treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD) but also revealed potential for idiosyncratic drug-induced
DataONE2019-09-21 更新90
Rx-TGx: Toxicogenomic Study Of Pharmaceuticals Using RNA-Seq
The robust transcriptional plasticity of liver mediated through xenobiotic receptors underlies its ability to respond rapidly and effectively to diverse chemical stressors. Thus, drug-induced gene exp
NIAID Data Ecosystem60
