Pax8

ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN epithelial cell differentiation (ortholog); metanephros development (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH Colorectal Neoplasms (ortholog); congenital hypothyroidism (ortholog); congenital nongoitrous hypothyroidism 2 (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred)

编码一种具有DNA结合（同源）特性的蛋白质；DNA结合转录激活酶活性，RNA聚合酶II特异性（同源）；序列特异性DNA结合（同源）；参与上皮细胞分化（同源）；肾发育（同源）；通过RNA聚合酶II的正向调控转录（同源）；与结直肠癌（同源）相关；先天性甲状腺功能减退症（同源）；先天性非睾发育甲状腺功能减退症2（同源）；推断存在于核质（推断）；细胞核（推断）