Transcriptome analysis of aortic valve tissues from hyperlipidemic and control mice with normal chow diet (chow) or western diet (WD)

We performed RNA sequencing of the aortic valves of C57BL/6J (the wild type with chow diet), Ldlr-/- (1. with chow diet, 2. with WD), and Apoe-/- mice (1. with chow diet, 2. with WD) to compare the overall transcriptomic characteristics within genetic differences (wild type, Ldlr-/-, Apoe-/-) or in dietary differences (chow diet versus WD). Overall design: mRNA profiles of aortic valve tissues from control mice (C57BL/6J) with normal chow diet (chow) and hyperlipidemic mice (Ldlr-/- and Apoe-/-) with normal chow diet (chow) or western diet (WD).