Different cholinergic cell groups in the basal forebrain regulate social interaction and social recognition memory

Here, we performed a selective elimination of cholinergic cell groups in the basal forebrain in mice to examine the role of cholinergic function in social interaction and social recognition memory by using the three-chamber test.
Elimination of cholinergic neurons was in the medial septum (MS) and vertical diagonal band of Broca (vDB) or in the nucleus basalis magnocellularis (NBM).