Crystal structure of MAP4K1 with a SMOL inhibitor
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Crystal structure of MAP4K1 with a SMOL inhibitor Descriptor: 4-[2,6-bis(fluoranyl)-4-(3-morpholin-4-ylpropylcarbamoylamino)phenoxy]-~{N}-[(4-methyl-1,2,5-oxadiazol-3-yl)methyl]-1~{H}-pyrrolo[2,3-b]pyridine-3-carboxamide, Mitogen-activated protein kinase kinase kinase kinase 1 Authors: Friberg, A. Deposit date: 2023-06-08 Release date: 2024-06-26 Last modified: 2025-01-29 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Discovery of BAY-405: An Azaindole-Based MAP4K1 Inhibitor for the Enhancement of T-Cell Immunity against Cancer. J.Med.Chem., 67, 2024
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2023-06-08
