Proliferative Indices of CD4+ peripheral blood lymphocytes from cavitary TB patients after 3�C5 weeks of treatment.

Proliferation indices (mean��SEM) were determined by flow cytometry (Fig. 3) following in vitro stimulation for 5 days with a T cell mitogen (SEB), Mumps antigen, or PPD at pretitered concentrations. Values given are those determined in the presence of antigen less that determined in the absence of antigen for the same specimen. The proliferation index in the absence of antigen was 0.2��0.4 for all specimens (N = 54). Significance p was determined using unpaired t tests at 95% confidence interval.