Human mitochondrial DNA (mtDNA) replication is first initiated at the origin of H-strand replication. The initiation depends on RNA primers generated by transcription from an upstream promoter (LSP).
Mutations in the mitochondrial genome (mtDNA) are ubiquitous in humans and can lead to a broad spectrum of disorders. However, due to the presence of multiple mtDNA molecules in the cell, co-existence
AMOVA results for three major haplogroups (AME, SEE and CE) of brown hare originating from Central-Eastern Europe, based on the 916-bp mtDNA sequences (cyt b + tRNA-Thr + tRNA-Pro + control region).
