Data from: Genotyping of Coxiella burnetii from domestic ruminants and human in Hungary: indication of various genotypes

Background: Information about the genotypic characteristic of Coxiella
burnetii from Hungary is lacking. The aim of this study is to describe the
genetic diversity of C. burnetii in Hungary and compare genotypes with
those found elsewhere. A total of 12 samples: (cattle, n = 6, sheep, n = 5
and human, n = 1) collected from across Hungary were studied by a 10-loci
multispacer sequence typing (MST) and 6-loci multiple-locus
variable-number of tandem repeat analysis (MLVA). Phylogenetic
relationships among MST genotypes show how these Hungarian samples are
related to others collected around the world. Results: Three MST genotypes
were identified: sequence type (ST) 20 has also been identified in
ruminants from other European countries and the USA, ST28 was previously
identified in Kazakhstan, and the proposed ST37 is novel. All MST
genotypes yielded different MLVA genotypes and three different MLVA
genotypes were identified within ST20 samples alone. Two novel MLVA types
0-9-5-5-6-2 (AG) and 0-8-4-5-6-2 (AF) (Ms23-Ms24-Ms27-Ms28-Ms33-Ms34) were
defined in the ovine materials correlated with ST28 and ST37. Samples from
different parts of the phylogenetic tree were associated with different
hosts, suggesting host-specific adaptations. Conclusions: Even with the
limited number of samples analysed, this study revealed high genetic
diversity among C. burnetii in Hungary. Understanding the background
genetic diversity will be essential in identifying and controlling
outbreaks.