File S1 - Kawasaki Disease-Specific Molecules in the Sera Are Linked to Microbe-Associated Molecular Patterns in the Biofilms

Supporting information. Text S1, Supporting Materials and Methods. Figure S1, LC-MS chromatograms and the detection rates and time course of 5 KD-specific molecules. Figure S2, Effects of biofilm formation, shaking time and various oils on the production of a KD-specific MAMP by LC-MS analysis. Figure S3, LC-MS and MS/MS analyses of 3 KD-specific molecules with IgG sepharose-binding activity. Table S1, Detection rates of spore-forming and pathogenic microbes in the oral cavity and upper respiratory tract of KD patients. Table S2, Presence of MAMPs in various microbes similar to serum KD-specific molecules. Table S3, Common MAMPs between the in vivo biofilms and sera in respective KD patients at the 2nd study. Table S4, Common MAMPs between the in vivo biofilms and sera, and microbes detected in respective KD patients at the 3rd study. Table S5, Sequences of oligonucleotide primers used for the amplification microbial genes.
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