We isolated mir-284 from a genetic screen for age-dependent axon degeneration in Drosophila melanogaster. mir-284 levels show a steep decline with aging. Therefore we embarked on a transcriptome-wide
Ageing is a complex process with common and distinct features across tissues. Unveiling the underlying processes driving ageing in individual tissues is indispensable to decipher the mechanisms of org
We performed a scRNAseq analysis conducted at the endpoint of our GBM mouse model. We compared differentially expressed up-regulated genes in p16Ink4a positive vs p16Ink4a negative malignant cells. Th
Background: In the event of an improvised nuclear device or radiological dirty bomb detonation large numbers of people will be exposed to radiation that would require a timely and accurate biodosimetr
Table containing 5,613 genes that are changing significantly (|log2FC| > 0.5 and FDR < 0.05) in at least one of the four comparisons related to the aging dataset (8wpi_main, 8wpi_old, term_young, term