KrasG12D/+ co-mutation alters the landscape of lung adenocarcinoma
收藏NIAID Data Ecosystem2026-03-13 收录
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Tumor pieces from Kras-mutant genetically engineered lung adenocarcinoma mouse models with loss Lkb1 and/or Keap1 were assessed.
Steady-state LC-MS analysis (M03818) was performed on tumor pieces; or normal lung pieces. Location is annotated.
13C,15N-Glutamine 15 minute pulse-labeling (M04050) of mice was performed at defined timepoints when tumor burden is known to be significantly progressed. Tumor pieces and plasma were isolated from n=5 mice/genotype.
Related to manuscript:
Best et al., Glutaminase inhibition impairs CD8 T cell activation in STK11/Lkb1 deficient lung cancer. Cell Metabolism, 2022
创建时间：
2022-04-21
