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Crystal structure of PqsR (MvfR) ligand-binding domain in complex with compound 1456

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Protein Data Bank Japan2024-06-12 更新2026-05-23 收录
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Crystal structure of PqsR (MvfR) ligand-binding domain in complex with compound 1456 Descriptor: Multiple virulence factor regulator MvfR, ~{N}-[[2-(3-chloranyl-4-propan-2-yloxy-phenyl)-1,3-thiazol-5-yl]methyl]-2-(trifluoromethyl)pyridin-4-amine Authors: Schmelz, S, Blankenfeldt, W. Deposit date: 2021-11-15 Release date: 2022-11-23 Last modified: 2024-06-12 Method: X-RAY DIFFRACTION (2.67 Å) Cite: Discovery and Optimization of Thiazole-Based Quorum Sensing Inhibitors as Potent Blockers of Pseudomonas Aeruginosa Pathogenicity Ssrn, 2024

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2021-11-15
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