A viral SAVED protein with ring nuclease activity subverts type III CRISPR defence

A viral SAVED protein with ring nuclease activity subverts type III CRISPR defence Descriptor: PHOSPHATE ION, SMODS-associated and fused to various effectors domain-containing protein Authors: McMahon, S.A, White, M.F, Orzechowski, M, Hoikkala, V, Chi, H, Gloster, T.M. Deposit date: 2025-05-16 Release date: 2025-07-02 Last modified: 2026-01-14 Method: X-RAY DIFFRACTION (1.79 Å) Cite: A viral SAVED protein with ring nuclease activity degrades the CRISPR second messenger cA4. Biochem.J., 482, 2025