Estimates are given as geometric means including the range over all five patients. Parameters without an estimate (–) were assumed to be fixed during the fitting procedure. Intermediate values of the
Background: Cases of undiagnosed pneumonia have emerged, and sequencing of respiratory samples indicated the presence of SARS-CoV-2 causing COVID-19. Patients with higher viral load and lower Ct val
For each virus strain, PR8 and PR8-PB1-F2(1918), the MLE initial viral titer (), infection rate constant (), death rate of productively infected cells (), viral release rate per infected cell (), and
Values of estimated individual parameters, , , , , features related to viral load, area under the curve, duration of infection, peak viral titer, time to peak viral titer, and daily viral load, calcul
