Transcriptomic study of NR8383 rat macrophages cells following exposure to TiO2 (NRCWE001)

To identify differentially expressed genes and key biological pathways that define toxicity following nanomaterial exposure, we performed microarray analyses on NR8383 macrophages exposed for 4 h to 3 cm²/cm² of rutile TiO2 (NRCWE001). This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement N°. 686098 Changes in gene expression in NR8383 cells incubated without (control) or with (3 cm²/cm²) of TiO2 (NRCWE001) for 4 h were measured. For each condition, four biological replicates were performed.