Transcriptomic data of inhibition of CDK12 in GBM12 cell line by SR-4835 treatment

This dataset contains transcriptomic profiles of the human glioblastoma cell line GBM12 following treatment with SR-4835, a selective CDK12 inhibitor. GBM12 cells were treated with SR-4835 or vehicle control for 24 hours, and total RNA was extracted for RNA sequencing. The study aims to elucidate transcriptional changes associated with CDK12 inhibition in glioblastoma and to identify downstream targets or pathways affected by SR-4835. Overall design: Comparative gene expression profiling analysis of RNA-seq data for GBM12 cells with DMSO (Condition1) or SR-4835 (Condition2) .