The summary of the results in GWAS, replication and combined datasets.

1GWAS dataset: 40 cases, 44 controls.2Replication dataset: chromosomes 3, 4, 9, 18, 23: 54 cases, 62 controls; chromosome 37: 81 cases, 88 controls.3Combined dataset: chromosomes 3, 4, 9, 18, 23: 94 cases, 106 controls; chromosome 37: 116 cases, 130 controls.4Frequency of the minor allele (based on GWAS controls) in affected individuals.5Frequency of the minor allele (based on GWAS controls) in unaffected individuals.