Background: Alcohol consumption is an established risk factor for colon cancer (CRC). Identifying cofactor(s) that modulate the effect of alcohol on colon inflammation and carcinogenesis could help ri
Background: We previously reported a gut microbiota metabolic dysbiosis and bacterial markers associated with colorectal cancer (CRC). However, it remains unclear whether these changes in the gut micr
Inhibition of the nonsense mediated decay (NMD) mechanism in cells results in stabilization of transcripts carrying premature translation termination codons. A strategy referred to as gene indentifica
The majority of colon carcinomas are known to develop in tubular adenomas through multi-stage carcinogenesis. Recently, we have reported a simple and reproducible method for the expression profiling u