Expression data from mice

Mice are sensitive to chemical substance and often used as an in vivo model for environmental toxicology research. We used microarrays to detail the global program of gene expression underlying cellularisation and identified distinct classes of up-regulated genes after treated with chemical substance. Mice were selected at early development stages for RNA extraction and hybridization on Affymetrix microarrays. We tested the expression data of mice treated with PM2.5 and/or melatonin.