Leydig Cells in Spermatogenesis-Deficient Testes Experience Stress, but Proliferate to Enhance Testosterone Synthesis II
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https://www.ncbi.nlm.nih.gov/sra/SRP527376
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资源简介：
We investigated somatic cell dynamics in testicular tissue lacking spermatogenesis using model mice with testis-specific deletion of the histone H3 variant gene H3t. Leydig cells in testes lacking spermatogenesis led to increased testosterone synthesis that occurred alongside a high inflammatory response and oxidative stress. Overall design: We generated H3t deletion mice that were used for testis section transcriptomics and spatial transcriptomics analyses of Leydig cells in testes with disruption of spermatogenesis.
创建时间：
2024-12-28
