iMN (Exp 2) - ALS, SMA and Control (unaffected) iMN cell lines differentiated from iPS cell lines using a long differentiation protocol - ATAC-seq

Epigenomic profiles using nuclei isolated from cryopreserved cultures of iPCS cells derived from amyotrophic lateral sclerosis (ALS), spinal muscular atrophy (SMA), and control (unaffected) subjects.The ATAC-seq technique detects open-chromatin regions and maps transcription factor binding events genome-wide by means of direct in vitro transposition of native chromatin.