The Nucleophilic Substitution Route. A Facile Method for the Fourfold Functionalization of the Methylene Bridges of Calix[4]arene
收藏NIAID Data Ecosystem2026-03-06 收录
下载链接：
https://figshare.com/articles/dataset/The_Nucleophilic_Substitution_Route_A_Facile_Method_for_the_Fourfold_Functionalization_of_the_Methylene_Bridges_of_Calix_4_arene/2996050
下载链接
链接失效反馈官方服务：
资源简介：
The radical bromination of p-tert-butylcalixarene tetramethyl ether was reinvestigated and the product (2b) characterized by X-ray crystallography.
The tetrabromo calixarene derivatives 2a or 2b react with alcohols (TFE, EtOH), azide, and 2-methylfuran under solvolytic conditions affording
calixarene derivatives functionalized at the four bridges. The reaction with alcohols and the aromatic compound proceeds in stereoselective
fashion and affords the rccc isomer of the tetrasubstituted product.
创建时间：
2016-02-29
