The mutational landscape of cancer’s vulnerability to ionizing radiation

Individual variant or wild type gene expression after constitutive transduction in immortalized lung ephithelial cells (BEAS-2B). The hypothesis is that variant gene expression is associated with radiation resistance or sensitivity. The results provide transcriptomic information on genes variants that conferred radiation resistance or sensitivity. Total mRNA obtained from BEAS2B cells transduced with the indicated gene variants and their corresponding wild type alleles.