Ras Affects Filamentous Growth in Saccharomyces cerevisiae Solely Through Regulation of Protein Kinase A

To assess the relative contributions of the PKA and MAPK pathways in Ras stimulation of filamentation, we examined the change in transcriptional profile following activation of Ras in strains in which one of these two pathways has been severed为评估Ras蛋白（Ras）刺激丝状化过程中蛋白激酶A（PKA，Protein Kinase A）与丝裂原活化蛋白激酶（MAPK，Mitogen-Activated Protein Kinase）通路的相对贡献，我们检测了在其中一条通路已被阻断的菌株中，Ras激活后的转录谱变化。