TEM-103/IRT-28 β-Lactamase, a New TEM Variant Produced by Escherichia coli BM4511
收藏PubMed Central2026-05-16 收录
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https://pmc.ncbi.nlm.nih.gov/articles/PMC128718/
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Clinical isolate Escherichia coli BM4511 was resistant to broad-spectrum penicillins in the presence or in the absence of β-lactamase inhibitors but remained susceptible to cephalosporins. Resistance was due to production of a new TEM-type β-lactamase, designated TEM-103/IRT-28, characterized by the Arg(275)Leu substitution and encoded by the ca. 62-kb pIP845 conjugative plasmid of the IncI1 incompatibility group.
提供机构：
American Society for Microbiology (ASM)
