Chromatin landscape in perinatal cardiomyocytes

In order to understand the transcriptional regulatory program of cardiomyocytes perinatal transition, we mapped chromatin accessibility, transcription-centered long-range chromatin interactions as well as gene expression in cardiomyocyte undergoing perinatal transition. Overall design: Gene expression profiles, chromatin accessibility genome-wide maps and chromatin interactions were obtained through RNA-sequencing, ATAC-sequencing and HiChIP sequencing of samples obtained from late fetal and neonatal cardiomyocytes.