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Analysis of the CD94 encoding gene Klrd1 revealed isogenic DBA/2 mice

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NIAID Data Ecosystem2026-03-10 收录
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https://www.ncbi.nlm.nih.gov/sra/ERP006830
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DBA/2J mice lack CD94 expression due to a deletion in the Klrd1 gene that occurred in the 1980s. Depending on the breeder we identified two DBA/2 variants with and without the deletion representing the old and new genotype that is still reflected in different batches of BXD lines and being a useful tool to study the role of CD94.
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2018-02-21
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