ETV5 silencing in bladder cancer cell line 97-7
收藏NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE122306
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We hypothesized that ETV5 may be a mediator of the oncogenic effects of mutant FGFR3 in bladder cancer cells ETV5 was silenced by shRNA in the bladder cancer cell line 97-7 to investigate effect on phenotype. To identify downstream gene targets of ETV5 we compared gene expression profiles in silenced and control cells. Two different hairpins targeting ETV5 were used (sh155 and sh1189) and expressed in 97-7 cells using a retroviral system. The gene expression profile of silenced cells was compared to the profile of the empty vector and scrambled controls. Each condition was repeated in triplicate. sh115 and sh1189 were pooled together for analysis; empty vector and scrambled controls were pooled together for analysis
创建时间：
2019-05-10
