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A Genome-wide RNAi screen identifies factors required for distinct stages of C. elegans piRNA biogenesis

ChEBI2014-04-01 更新2026-07-21 收录

piRNA生物合成

线虫RNA干扰筛选

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-53970 数据链接链接失效反馈

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资源简介：

A Genome-wide RNAi screen identifies factors required for distinct stages of C. elegans piRNA biogenesis

应用场景：

创建时间：

2014-04-01

piRNA生物合成

斑马鱼发育

In this study, we generated zebrafish pld6 knockouts and found that the pld6-null mutants developed as infertile males, with testes containing no germ cells. Pld6 is considered to be a candidate ribon

NIAID Data Ecosystem130

An Ancient Transcription Factor Initiates the Burst of piRNA Production During Early Meiosis in Mouse Testes (RNA-Seq)

piRNA生物合成

精子发生

Animal germ cells produce PIWI-interacting RNAs (piRNAs), small silencing RNAs that suppress transposons and enable gamete maturation. Mammalian transposon-silencing piRNAs accumulate early in spermat

NIAID Data Ecosystem80

PETISCO is a novel protein complex required for 21U RNA biogenesis and embryonic viability

piRNA生物合成

早期胚胎发育

Piwi proteins are important for germ cell development and function in almost all animals studied thus far. These proteins are guided to specific targets, such as transposable elements, by small guide

NIAID Data Ecosystem60

Zucchini dependent and independent pre-piRNA generation and their sequence features in silkworms. Bombyx mori strain:BmN cell

piRNA生物合成

RNA序列基序分析

This project aims to reveal a characteristic nucleotide motif in precursor RNAs preferentially cleaved by BmZuc.

NIAID Data Ecosystem110

Epigenetic control of transposable elements in the mouse male germ line by Tex15. Epigenetic control of transposable elements in the mouse male germ line by Tex15

piRNA生物合成

转座子沉默

The piRNA biogenesis was evaluated in the mouse testes lacking TEX15. Total small RNAs, MILI-, and MIWI2-associated small RNAs from control (Tex15+/-) and Tex15(-/-) knock-out testes were sequenced. D

NIAID Data Ecosystem70

A Genome-wide RNAi screen identifies factors required for distinct stages of C. elegans piRNA biogenesis

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