Characteristics of Studies Investigating CVD Related to ADT.

Abbreviations: LOE = level of evidence; CVD = cardiovascular disease; ADT = androgen deprivation therapy;GnRH = gonadotropin-releasing hormone (leuteinizing hormone releasing hormone, LHRH); AA = oral antiandrogens; RP = Radical prostatectomy/Curative Treatment; WW/AS = watchful waiting (WW)/active surveillance (AS); AMI = Acute Myocardial Infarction; CHD = Coronary Heart Disease; HRs = Hazard Ratios; RRs = Risk Ratios; NA = not applicable; NPCR = National Prostate Cancer Register; SEER = Surveillance, Epidemiology and End Results Medicare data; GPRD = UK General Practice Research Database; ICES = Institute for Clinical Evaluative Sciences.a mean or median.b compared with WW/AS.c The HR/RR was directly given in the publication.d Combined estimates from all types of ADT with random effects meta-analysis.Characteristics of Studies Investigating CVD Related to ADT.