Neural crest differentiation

Gene regulatory network model of cranial neural crest cell (CNCC) development, adaped from PMID: 19575671. Most interactions in the model are proposed to regulate transcription of core factors involved involved in neural crest and downstream progenitor specification. Transcriptional regulation arrows are proposed to promote transcription, unless a graphical T-bar is present at the end of the arrow (commented to be inhibitors of transcriptional regulation). Additional gene information was obtained from http://www.ncbi.nlm.nih.gov/books/NBK53143 When citing thies pathway, please reference the source publication (PMID: 19575671).

颅神经嵴细胞（CNCC）发育的基因调控网络模型，源自PMID: 19575671。模型中大多数相互作用被提议为调节参与神经嵴及其下游祖细胞分化的核心因子的转录。转录调控箭头被提议以促进转录，除非箭头末端存在图形化的T形符号（注释为转录调控的抑制剂）。额外的基因信息来源于http://www.ncbi.nlm.nih.gov/books/NBK53143。在引用此通路时，请参考原始发表文献（PMID: 19575671）。