NASH LiverModel transcriptome

Mitochondrial reactive oxygen species (mROS) is central to normal physiology, but their excessive production correlates with the etiology of many human metabolic pathologies. We assessed in human liver biopsies from patients with non-alcoholic liver disease with different grades of liver steatosis and fibrosis the gene expression of ubiquinone genes and we uncover a positive relationship between QH2/Q ratio and the steatosis grade. progresssion. Transcriptome analysis on liver biopsies from patients at different steatosis stages