Separating lipid-carrying particles from body fluids is challenging and complicates studies of extracellular vesicles (EV) and lipoprotein particles (LPP) as disease biomarkers. In this study, we asse
Tandem mass tag (TMT)-based mass spectrometry (MS) enables deep proteomic profiling of more than 10,000 proteins in complex biological samples but requires up to 100 μg protein in starting materials d
IntroductionChronic myeloid leukemia (CML) is driven by the BCR::ABL1 fusion gene. Although tyrosine kinase inhibitors (TKIs) have transformed outcomes, treatment resistance persists. Plasma extracell
