2-hydroxyglutarate modulates histone methylation using both RNA/ChIP-seq. 2-hydroxyglutarate modulates histone methylation using both RNA/ChIP-seq
收藏NIAID Data Ecosystem2026-05-01 收录
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2-hydroxyglutarate (2-HG) is an oncometabolite accumulating in certain cancers and some neurometabolic diseases. In cancers 2-HG accumulation is induced by a gain-of-function mutation in isocitrate dehydrogenase (IDH) genes, leading to conversion of alpha-ketoglutarate (a-KG) into 2-HG
创建时间：
2023-04-15
