Paclitaxel plus Cirmtuzumab Achieves Greater Clearance of Patient-derived Xenografts By Targeting ROR1+ Breast Cancer Stem Cells
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE108632
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We applied high-throughput sequence to identify signaling pathways, stem cell gene signature or target genes of BMI1 that were affected by our newly development humainzed anti-ROR1 antibody (cirmtuzumab) in breast cancer patient-derived xenograft (PDX) mice model Examination of 8 PDX samples isolated from control-treated mice (N=4) versus cirmtuzumab-treated mice (N=4)
创建时间:
2019-03-21



