scRNA-seq and spatial transcriptomics of MIBC across different ICB exposure and response state
收藏Mendeley Data2026-04-09 收录
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https://data.mendeley.com/datasets/hrtj23vgfb/1
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资源简介：
To explore how TME components regulate tumor cell fate plasticity through intricate cellular interaction networks, and thereby induce ICB resistance in MIBC, we performed scRNA-seq on 11 tumor samples obtained from 6 MIBC patients, covering distinct anatomical regions. Additionally, we conducted spatial transcriptomics on freshly collected specimens from 4 of these patients. We performed multiple bioinformatic analysis and employed in vitro functional assays to validate our findings.
提供机构：
Shanghai General Hospital Urology Center
