The structure of PRMT4 in complex with YD1305

The structure of PRMT4 in complex with YD1305 Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-{[2-(benzylcarbamamido)ethyl](3-{[(4'-chloro[1,1'-biphenyl]-3-yl)methyl]amino}propyl)amino}-5'-deoxyadenosine, CALCIUM ION, ... Authors: Bush, M, Noinaj, N, Deng, Y, Huang, R. Deposit date: 2025-04-06 Release date: 2026-05-13 Last modified: 2026-05-27 Method: X-RAY DIFFRACTION (2.11 Å) Cite: Tailoring PRMT Inhibition: Shifting PRMT7 Selectivity to PRMT4 through "T-Shape" Strategy and "Linker-Specific" Preferences. J.Med.Chem., 69, 2026